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Agouti-related Protein (AGRP) (83-132) Amide (human) (TFA)

Product Specifications

UNSPSC Description

Agouti-related Protein (AGRP) (83-132) Amide (human) TFA is a fragment of agouti-related protein (AGRP) which is a protein found in abundance in the arcuate nucleus of the hypothalamus. AgRP primarily acts as an inverse agonist for the melanocortin-4 receptor (MC4R) to increase food intake[1][2].

Target Antigen

Melanocortin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein;Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/agouti-related-protein-agrp-83-132-amide-human-tfa.html

Purity

96.96

Solubility

10 mM in DMSO

Smiles

[SSRRCVRLHESCLGQQVPCCDPCATCYCRFFNAFCYCRKLGTAMNPCSRT-NH2 (Disulfide bridge: Cys1-Cys4; Cys2-Cys6; Cys3-Cys9; Cys5-Cys10; Cys7-Cys8) (TFA salt)]

Molecular Weight

5790.62 (free acid)

References & Citations

[1]Donald W. Pfaff, et al. Chapter 1 - Hormones Can Facilitate or Suppress Behaviors. Principles of Hormone/Behavior Relations (Second Edition). Academic Press, 2018, Pages 3-26, ISBN 9780128113714.|[2]Tang-Christensen M, et al. Central administration of ghrelin and agouti-related protein (83-132) increases food intake and decreases spontaneous locomotor activity in rats. Endocrinology. 2004 Oct;145(10):4645-52.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P3561A/Agouti-related-Protein-AGRP-83-132-Amide-human-TFA-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P3561A/Agouti-related-Protein-AGRP-83-132-Amide-human-TFA-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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