Rebamipide mofetil
Rebamipide mofetil is an orally active proagent of Rebamipide (OPC12759) . Rebamipide is a mucoprotective agent. Rebamipide induces COX-2 expression, increases PGE2 levels, and enhances gastric mucosal defense in a COX-2-dependent manner[1].
Product Specifications
CAS Number
[1527495-76-6]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/rebamipide-mofetil.html
Purity
96.12
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C=C(CC(C(OCCN2CCOCC2)=O)NC(C3=CC=C(C=C3)Cl)=O)C4=C(N1)C=CC=C4
Molecular Formula
C25H26ClN3O5
Molecular Weight
483.94
Precautions
H302, H315, H319
References & Citations
[1]Cho, Eui Hwan, et al.Pharmaceutical composition comprising rebamipide precursor for oral administration for preventing or treating immune disease and metabolic disease.WO2017138717A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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