(Z) -Oleyloxyethyl phosphorylcholine

(Z) -Oleyloxyethyl phosphorylcholine ((Z) -OPC) is an isomer of Oleyloxyethyl phosphorylcholine (OPC) . Oleyloxyethyl phosphorylcholine is an inhibitor of secreted Phospholipase A2 (sPLA2), which is involved in the biosynthesis of proinflammatory lipid media. Oleyloxyethyl phosphorylcholine can be used to study inflammatory diseases. Oleyloxyethyl phosphorylcholine also modified the red blood membrane and was used to bind the oxygen-carrying liquid perfluorocarbons as an antivenom agent to reduce toxin-induced hemolysis[1][2].

Product Specifications

CAS Number

[84601-19-4]

UNSPSC

12352211

Target

Phospholipase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/z-oleyloxyethyl-phosphorylcholine.html

Concentration

20.94 mM * 0.5 mL in Ethanol

Purity

98.0

Solubility

10 mM in DMSO

Smiles

CCCCCCCC/C=C\CCCCCCCCOCCOP(OCC[N+](C)(C)C)([O-])=O

Molecular Formula

C25H52NO5P

Molecular Weight

477.66

References & Citations

[1]Hope WC, et al. Secretory phospholipase A2 inhibitors and calmodulin antagonists as inhibitors of cytosolic phospholipase A2. Agents Actions. 1993;39 Spec No:C39-42. |[2]Yang Zhe, et al. Oxygen-carrying bionic nano antidote and its preparation method and application in preparation of anti snake venom drug. China, CN113509488 A. 2021-10-19.