5-Hydroxy-8-methoxypsoralen

5-Hydroxy-8-methoxypsoralen (5-Hydroxyxanthotoxin) is a metabolite of Xanthotoxin. Xanthotoxin is a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450), is an agent used to treat psoriasis, eczema, vitiligo and some cutaneous Lymphomas in conjunction with exposing the skin to sunlight[1].

Product Specifications

CAS Number

[7471-73-0]

Product Name Alternative

5-Hydroxyxanthotoxin

UNSPSC

12352005

Target

Drug Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/5-hydroxy-8-methoxypsoralen.html

Purity

99.82

Solubility

10 mM in DMSO

Smiles

O=C1C=CC2=C(O)C3=C(OC=C3)C(OC)=C2O1

Molecular Formula

C12H8O5

Molecular Weight

232.19

References & Citations

[1]Alsharari SD, et al. Pharmacokinetic and Pharmacodynamics Studies of Nicotine After Oral Administration in Mice: Effects of Methoxsalen, a CYP2A5/6 Inhibitor. Nicotine Tob Res. 2014 Jan;16 (1) :18-25.