OICR-8268-acrylic acid-amino-PEG9-amine
Selected Variant
HY-169391
Size: 1 Each
OICR-8268-acrylic acid-amino-PEG9-amine is an E3 ligase ligand-linker conjugate. OICR-8268-acrylic acid-amino-PEG9-amine can be used to synthesize OICR41114.
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/oicr-8268-acrylic-acid-amino-peg9-amine.html
Smiles
O=C(/C=C/C1=C(C(C(N[C@H](C2=CC=C(C(Cl)=C2)F)CC(N)=O)=O)=CN1)C3=C(C=C(C=C3)Cl)F)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN
Molecular Formula
C43H59Cl2F2N5O12
Molecular Weight
946.86
References & Citations
[1]Mabanglo MF, et al. Crystal structures of DCAF1-PROTAC-WDR5 ternary complexes provide insight into DCAF1 substrate specificity. Nat Commun. 2024 Nov 23;15 (1) :10165.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Price
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