Frovatriptan

Frovatriptan is a potent 5-HT1B//D receptor agonist and has the highest 5-HT1B potency in the triptan class. Frovatriptan is apparently cerebroselective. Frovatriptan is efficacious and even superior in some endpoints also when taken during the headache phase in migraine attacks with aura[1].

Product Specifications

CAS Number

[158747-02-5]

Product Name Alternative

(R) -Frovatriptan; SB 209509; VML 251

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/frovatriptan.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC2=C(NC3=C2C[C@H](NC)CC3)C=C1)N

Molecular Formula

C14H17N3O

Molecular Weight

243.30

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]Stefan Evers, et al. Efficacy of frovatriptan as compared to other triptans in migraine with aura.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Launched

Isoform

5-HT1 Receptor

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