Human Factor XII (Factor 12) Deficient Serum

<strong>Human Factor XII (Factor 12) Deficient Serum</strong>_x000D_ <strong>Catalog number:</strong> B2015449_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 mL_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> N/A_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> Coagulation Factor XII, Coagulation Factor 12, F12, FXII_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Hopp S, Albert-Weissenberger C, Mencl S, Bieber M, Schuhmann MK, Stetter C, Nieswandt B, Schmidt PM, Monoranu CM, Alafuzoff I, Marklund N, Nolte MW, Sirén AL, Kleinschnitz C. Targeting coagulation factor XII as a novel therapeutic option in brain trauma Ann Neurol. 2016 Jun;79(6):970-82._x000D_ 2: Golas A, Yeh CH, Pitakjakpipop H, Siedlecki CA, Vogler EA. A comparison of blood factor XII autoactivation in buffer, protein cocktail, serum, and plasma solutions Biomaterials. 2013 Jan;34(3):607-20._x000D_ 3: Yamada H, Kato EH, Kobashi G, Ebina Y, Shimada S, Morikawa M, Yamada T, Sakuragi N, Fujimoto S. Recurrent pregnancy loss: etiology of thrombophilia Semin Thromb Hemost. 2001;27(2):121-9._x000D_ 4: Cochrane CG, Wuepper KD, Aiken BS, Revak SD, Spiegelberg HL. The interaction of Hageman factor and immune complexes J Clin Invest. 1972 Oct;51(10):2736-45._x000D_ 5: Vaziri ND, Ngo JL, Ibsen KH, Mahalwas K, Roy S, Hung EK. Deficiency and urinary losses of factor XII in adult nephrotic syndrome Nephron. 1982;32(4):342-6._x000D_ 6: Marcum JA, Kline DL. Nonplasminogen-dependent protease in human plasma Blood. 1979 Sep;54(3):607-13._x000D_ 7: Braat EA, Dooijewaard G, Rijken DC. Fibrinolytic properties of activated FXII Eur J Biochem. 1999 Aug;263(3):904-11._x000D_ 8: Saito H, Ratnoff OD. Alteration of factor VII activity by activated Fletcher factor (a plasma kallikrein): a potential link between the intrinsic and extrinsic blood-clotting systems J Lab Clin Med. 1975 Mar;85(3):405-15._x000D_ 9: Yang A, Zhou J, Wang B, Dai J, Colman RW, Song W, Wu Y. A critical role for plasma kallikrein in the pathogenesis of autoantibody-induced arthritis FASEB J. 2017 Dec;31(12):5419-5431._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/6813992">10: Thompson AR. Factor XII and other hemostatic protein abnormalities in nephrotic syndrome patients Thromb Haemost. 1982 Aug 24;48(1):27-32.</a>_x000D_ _x000D_ <strong>Products Related to Human Factor XII (Factor 12) Deficient Serum can be found at</strong> <a href="https://moleculardepot.com/product-category/Biofluids/"> Biofluids</a>