AXL, Human (D266N, HEK293, His)

AXL protein is a receptor tyrosine kinase that mediates signals by binding to GAS6 and regulates cell survival, proliferation, migration and differentiation. After ligand binding, AXL dimerizes and autophosphorylates, activating downstream molecules, such as PI3 kinase subunits, GRB2, PLCG1, etc. AXL Protein, Human (D266N, HEK293, His) is the recombinant human-derived AXL protein, expressed by HEK293 , with C-10*His labeled tag and D266N, , , , mutation. The total length of AXL Protein, Human (D266N, HEK293, His) is 426 a.a., with molecular weight of 48.9 kDa.

APRGTQAEES PFVGNPGNIT GARGLTGTLR CQLQVQGEPP EVHWLRDGQI LELADSTQTQ VPLGEDEQDD WIVVSQLRIT SLQLSDTGQY QCLVFLGHQT FVSQPGYVGL EGLPYFLEEP EDRTVAANTP FNLSCQAQGP PEPVDLLWLQ DAVPLATAPG HGPQRSLHVP GLNKTSSFSC EAHNAKGVTT SRTATITVLP QQPRNLHLVS RQPTELEVAW TPGLSGIYPL THCTLQAVLS NDGMGIQAGE PDPPEEPLTS QASVPPHQLR LGSLHPHTPY HIRVACTSSQ GPSSWTHWLP VETPEGVPLG PPENISATRN GSQAFVHWQE PRAPLQGTLL GYRLAYQGQD TPEVLMDIGL RQEVTLELQG DGSVSNLTVC VAAYTAAGDG PWSLPVPLEA WRPGQAQPVH QLVKEPSTPA FSWPWW