Arcopilin A

Arcopilin A (compound Arcopilin A (1) ) is an antibacterial agent. Arcopilin A has weak inhibitory effects on fungal pathogens and Gram-positive bacteria, with IC50 values of 8.9 μg/mL and 14 μg/mL for cells KB-3-1 and L929, but it can effectively destroy preformed biofilms of Staphylococcus aureus. Arcopilin A can enhance the activities of gentamicin (GM; HY-K1050) and vancomycin (Vac; HY-B0671) by 115 and 31 times, respectively[1].

Product Specifications

UNSPSC

12352005

Target

Bacterial

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/arcopilin-a.html

Smiles

CC([C@@H](C[C@H](C[C@@H](C(C1=C(/C(NC1=O)=C/C2=CC=CC=C2)O)=O)C)C)C)=O

Molecular Formula

C22H27NO4

Molecular Weight

369.45

References & Citations

[1]Esteban Charria-Girón, et al. Arcopilins: A New Family of Staphylococcus aureus Biofilm Disruptors from the Soil Fungus Arcopilus navicularis. J Med Chem. 2024 Aug 14.