Tolnaftate
Tolnaftate (NP-27) is a synthetic thiocarbamate used as an anti-fungal agent. .
Product Specifications
CAS Number
2398-96-1
Product Name Alternative
NP-27
UNSPSC
12352005
Hazard Statement
H302
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Tolnaftate.html
Concentration
10mM
Purity
99.28
Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic)
Smiles
S=C(OC1=CC=C2C=CC=CC2=C1)N(C)C3=CC=CC(C)=C3
Molecular Formula
C19H17NOS
Molecular Weight
307.41
Precautions
H302
References & Citations
[1]Ryder, N.S., I. Frank, and M.C. Dupont, Ergosterol biosynthesis inhibition by the thiocarbamate antifungal agents tolnaftate and tolciclate. Antimicrob Agents Chemother, 1986. 29 (5) : p. 858-60.|[2]Georgopapadakou, N.H. and A. Bertasso, Effects of squalene epoxidase inhibitors on Candida albicans. Antimicrob Agents Chemother, 1992. 36 (8) : p. 1779-81.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
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