Tolnaftate

Tolnaftate (NP-27) is a synthetic thiocarbamate used as an anti-fungal agent. .

Product Specifications

CAS Number

[2398-96-1]

Product Name Alternative

NP-27

UNSPSC

12352005

Hazard Statement

H302

Target

Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Tolnaftate.html

Concentration

10mM

Purity

99.28

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic)

Smiles

S=C(OC1=CC=C2C=CC=CC2=C1)N(C)C3=CC=CC(C)=C3

Molecular Formula

C19H17NOS

Molecular Weight

307.41

Precautions

H302

References & Citations

[1]Ryder, N.S., I. Frank, and M.C. Dupont, Ergosterol biosynthesis inhibition by the thiocarbamate antifungal agents tolnaftate and tolciclate. Antimicrob Agents Chemother, 1986. 29 (5) : p. 858-60.|[2]Georgopapadakou, N.H. and A. Bertasso, Effects of squalene epoxidase inhibitors on Candida albicans. Antimicrob Agents Chemother, 1992. 36 (8) : p. 1779-81.