IHR-1
Product Specifications
UNSPSC Description
IHR-1 is a cell membrane impermeable Smo antagonist[1].
Target Antigen
Smo
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ihr-1.html
Purity
98.05
Solubility
DMSO : 20.83 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C(C1=C(C=CC(Cl)=C1)Cl)NC(C=C2)=CC=C2NC(C3=C(C=CC(Cl)=C3)Cl)=O
Molecular Weight
454.13
References & Citations
[1]Chih-Wei Fan, et al. The Hedgehog pathway effector smoothened exhibits signaling competency in the absence of ciliary accumulation. Chem Biol. 2014 Dec 18;21(12):1680-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-110240/IHR-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-110240/IHR-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
548779-60-8
Available Sizes
Curated Selection
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