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TNKS-2-IN-2

TNKS-2-IN-2 is a potent and selective inhibitor of TNKS2 with an IC50 of 22 nM[1].

Product Specifications

CAS Number

2719726-91-5

UNSPSC

12352005

Target

PARP

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tnks-2-in-2.html

Purity

99.47

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

COC1=C(C(OC)=CC(C(NC2=CC=C(C=C2)NC(C3=CNC4=CC=CC=C4C3=O)=O)=O)=C1)OC

Molecular Formula

C26H23N3O6

Molecular Weight

473.48

References & Citations

[1]Zhang X, et al. Design, synthesis, and biological activity evaluation of new tankyrase-2 directed inhibitors. Chem Biol Drug Des. 2023 Oct 10.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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