TNKS-2-IN-2
TNKS-2-IN-2 is a potent and selective inhibitor of TNKS2 with an IC50 of 22 nM[1].
Product Specifications
CAS Number
2719726-91-5
UNSPSC
12352005
Target
PARP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tnks-2-in-2.html
Purity
99.47
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
COC1=C(C(OC)=CC(C(NC2=CC=C(C=C2)NC(C3=CNC4=CC=CC=C4C3=O)=O)=O)=C1)OC
Molecular Formula
C26H23N3O6
Molecular Weight
473.48
References & Citations
[1]Zhang X, et al. Design, synthesis, and biological activity evaluation of new tankyrase-2 directed inhibitors. Chem Biol Drug Des. 2023 Oct 10.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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