ERα/ERβ antagonist-1
ERα/ERβ antagonist-1 (Compound 10) is partial antagonists of ERα and ERβ. ERα/ERβ antagonist-1 reduces ERα and ERβ activity in a dose-dependent manner in HepG2 liver cells[1].
Product Specifications
CAS Number
[2482778-93-6]
UNSPSC
12352005
Target
Estrogen Receptor/ERR
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/erα-erβ-antagonist-1.html
Smiles
OC1=C(CC=C)C=C(C2=C(OC(CCC)=O)C=CC(CC=C)=C2)C=C1
Molecular Formula
C22H24O3
Molecular Weight
336.42
References & Citations
[1]Tinivella A, et al. Exploring Biological Targets of Magnolol and Honokiol and their Nature-Inspired Synthetic Derivatives: In Silico Identification and Experimental Validation of Estrogen Receptors. J Nat Prod. 2024 Nov 22;87 (11) :2568-2579.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ERα; ERβ
Curated Selection
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