MTMRC rabbit pAb

Phosphatidylinositide 3-kinase-derived membrane-anchored phosphatidylinositides, such as phosphatidylinositol 3-phosphate (PtdIns (3)P), regulate diverse cellular processes. The protein encoded by this gene functions as an adaptor subunit in a complex with an active PtdIns (3)P 3-phosphatase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014],

Product Specifications

Background

Phosphatidylinositide 3-kinase-derived membrane-anchored phosphatidylinositides, such as phosphatidylinositol 3-phosphate (PtdIns (3) P), regulate diverse cellular processes. The protein encoded by this gene functions as an adaptor subunit in a complex with an active PtdIns (3) P 3-phosphatase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]

UniProt

Q9C0I1

Swiss Prot

Q9C0I1

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from human MTMRC AA range: 523-573

Target

MTMRC

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA; IHC

Concentration

1 mg/ml

Dilution

WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Buffer

-20°C/1 year

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

Cytoplasm . Sarcoplasmic reticulum . Cytoplasm, myofibril, sarcomere . Localizes to punctate vesicles when associated with MTM1 (PubMed:12847286) . Localizes to triads, a structure formed by a T tubule and two sarcoplasmic reticulum terminal cisterna (By similarity) . In skeletal muscles, co-localizes with MTM1 in the sarcomere (By similarity) . Partially localizes to the sarcoplasmic reticulum in skeletal muscles (By similarity) . .