PSB-1434
PSB-1434 is a selective monoamine oxidase B (MAO-B) inhibitor with an IC50 of 1.59 nM. PSB-1434 shows >6000-fold selective for MAO-B than MAO-A[1].
Product Specifications
CAS Number
[1619884-65-9]
Product Name Alternative
1,25-Dihydroxyvitamin D3-13C12,1-hydroxycholecalciferol; 1.alpha.-Hydroxyvitamin D3,1,25-Dihydroxyvitamin D3-d12
UNSPSC
12352005
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/psb-1434.html
Purity
98.05
Solubility
DMSO : 6.25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(NC1=CC=C(C(F)=C1)F)C2=CC3=C(C=C2)NN=C3
Molecular Formula
C14H9F2N3O
Molecular Weight
273.24
References & Citations
[1]Tzvetkov NT, et al., Indazole- and indole-5-carboxamides: selective and reversible monoamine oxidase B inhibitors with subnanomolar potency. J Med Chem. 2014 Aug 14;57 (15) :6679-703.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAO-B
Available Sizes
Curated Selection
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