Meglutol-d3
Meglutol-d3 is the deuterium labeled Meglutol[1]. Meglutol is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids, and inhibits the activity of hydroxymethylglutarryl CoA reductases, which is the rate limiting enzyme in the biosynthesis of cholesterol.
Product Specifications
CAS Number
59060-36-5
Product Name Alternative
Dicrotalic acid-d3; 3-Hydroxy-3-methylglutaric acid-d3
UNSPSC
12352211
Target
Autophagy; Endogenous Metabolite; HMG-CoA Reductase (HMGCR)
Type
Isotope-Labeled Compounds
Related Pathways
Autophagy; Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Purity
98.04
Solubility
Methanol : 100 mg/mL (ultrasonic)
Smiles
OC(CC(C([2H])([2H])[2H])(O)CC(O)=O)=O
Molecular Formula
C6H7D3O5
Molecular Weight
165.16
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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