Telotristat ethyl
Product Specifications
Product Name Alternative
LX1032; LX1606
UNSPSC Description
Telotristat ethyl (LX1032) is a novel, orally-delivered inhibitor of tryptophan hydroxylase that reduces serotonin production.
Target Antigen
Tryptophan Hydroxylase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/lx1606.html
Purity
99.79
Solubility
DMSO : ≥ 101.5 mg/mL
Smiles
N[C@@H](CC1=CC=C(C2=NC(N)=NC(O[C@H](C3=CC=C(Cl)C=C3N4N=C(C)C=C4)C(F)(F)F)=C2)C=C1)C(OCC)=O
Molecular Weight
574.98
References & Citations
[1]Tamas Oravecz, et al. LX1606 (aka LX1032), a Novel Inhibitor of Serotonin Synthesis, Alleviates Development of Inflammatory Bowel Disease in a Preclinical Model.|[2]Margolis, K.G., et al., Pharmacological reduction of mucosal but not neuronal serotonin opposes inflammation in mouse intestine. Gut, 2013.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-13055A/Telotristat-ethyl-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-13055A/Telotristat-ethyl-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
1033805-22-9
Available Sizes
Curated Selection
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