Cycloposine
Cycloposine is a steroidal alkaloid that can be found in the roots and rhizomes of Veratrum californicum. Cycloposine is also a teratogenic compound that may induce cyclopia in pregnant Mianyang embryos[1].
Product Specifications
CAS Number
23185-94-6
UNSPSC
12352005
Hazard Statement
H301, H360
Target
Others
Type
Natural Products
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/cycloposine.html
Concentration
10mM
Purity
98.0
Solubility
DMSO : 46.67 mg/mL (ultrasonic)
Smiles
CC1=C(C[C@@]2([H])[C@@]3([H])CC=C4[C@@]2(CC[C@@H](C4)O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)O)CO)C)[C@@]3([H])CC[C@]16O[C@@]7([H])[C@](NC[C@H](C7)C)([H])[C@H]6C
Molecular Formula
C33H51NO7
Molecular Weight
573.76
Precautions
H301, H360
References & Citations
[1]Chandler CM, et, al. Improved extraction and complete mass spectral characterization of steroidal alkaloids from Veratrum californicum. Nat Prod Commun. 2013 Aug;8 (8) :1059-64.|[2]Keeler RF. Teratogenic compounds of Veratrum californicum (Durand) . VII. The structure of the glycosidic alkaloid cycloposine. Steroids. 1969 May;13 (5) :579-88.|[3]Heretsch P, et al. Cyclopamine and hedgehog signaling: chemistry, biology, medical perspectives. Angew Chem Int Ed Engl. 2010 May 3;49 (20) :3418-27.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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