Tariquidar (dimesylate)
Tariquidar dimesylate (XR9576 dimesylate) is a P-glycoprotein (P-gp) inhibitor. Tariquidar dimesylate increases the concentration of the drug in the brain by binding to P-glycoprotein, preventing it from transporting the drug from inside to outside the brain. Tariquidar dimesylate can be used in the study of blood-brain barrier penetration and multidrug resistance[1].
Product Specifications
CAS Number
625375-84-0
Product Name Alternative
XR9576 (dimesylate)
UNSPSC
12352005
Target
P-glycoprotein
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease; Others
Assay Protocol
https://www.medchemexpress.com/tariquidar-dimesylate.html
Smiles
O=C(NC1=CC(OC)=C(C=C1C(NC2=CC=C(C=C2)CCN3CC4=C(CC3)C=C(C(OC)=C4)OC)=O)OC)C5=CC6=CC=CC=C6N=C5.OS(=O)(C)=O.OS(=O)(C)=O
Molecular Formula
C38H38N4O6.2CH4O3S.H2O
Molecular Weight
838.94
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
Frequently Asked Questions
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