Darinaparsin

Darinaparsin (ZIO-101), an organic arsenical, is a mitochondrial-targeted agent. Darinaparsin induces apoptosis in ancer cells, and has anticancer effects[1].

Product Specifications

CAS Number

[69819-86-9]

Product Name Alternative

ZIO-101; S-Dimethylarsino-glutathione

UNSPSC

12352211

Hazard Statement

H302-H315-H319-H335

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/darinaparsin.html

Purity

98.0

Solubility

H2O : 62.5 mg/mL (ultrasonic)

Smiles

O=C(NCC(O)=O)[C@H](CS[As](C)C)NC(CC[C@H](N)C(O)=O)=O

Molecular Formula

C12H22AsN3O6S

Molecular Weight

411.31

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Nitu Bansal, et al. Darinaparsin inhibits prostate tumor-initiating cells and Du145 xenografts and is an inhibitor of hedgehog signaling. Mol Cancer Ther. 2015 Jan;14 (1) :23-30.