Darinaparsin
Darinaparsin (ZIO-101), an organic arsenical, is a mitochondrial-targeted agent. Darinaparsin induces apoptosis in ancer cells, and has anticancer effects[1].
Product Specifications
CAS Number
69819-86-9
Product Name Alternative
ZIO-101; S-Dimethylarsino-glutathione
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/darinaparsin.html
Purity
98.0
Solubility
H2O : 62.5 mg/mL (ultrasonic)
Smiles
O=C(NCC(O)=O)[C@H](CS[As](C)C)NC(CC[C@H](N)C(O)=O)=O
Molecular Formula
C12H22AsN3O6S
Molecular Weight
411.31
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Nitu Bansal, et al. Darinaparsin inhibits prostate tumor-initiating cells and Du145 xenografts and is an inhibitor of hedgehog signaling. Mol Cancer Ther. 2015 Jan;14 (1) :23-30.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
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