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Savoxepin (mesylate)

Savoxepin mesylate is a D2 dopamine receptor (D2 Dopamine Receptor) antagonist with antipsychotic activity. Savoxepin mesylate selectively blocks dopamine D2 receptors in the hippocampus while having no significant effect on D2 receptors in the striatum. This selective blockade helps reduce the risk of extrapyramidal side effects (EPS) [1].

Product Specifications

CAS Number

79262-47-8

UNSPSC

12352005

Target

Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/savoxepin-mesylate.html

Smiles

N#CC1=CC=C2OC3=CC=CC=C3C(CCN(CC4)CC5CCCC5)=C4C2=C1.CS(=O)(O)=O

Molecular Formula

C26H30N2O4S

Molecular Weight

466.59

References & Citations

[1]Bischoff S, et al. Blockade of hippocampal dopamine (DA) receptors: a tool for antipsychotics with low extrapyramidal side effects. Prog Neuropsychopharmacol Biol Psychiatry. 1988;12 (4) :455-67.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 2

Frequently Asked Questions

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