Savoxepin (mesylate)
Savoxepin mesylate is a D2 dopamine receptor (D2 Dopamine Receptor) antagonist with antipsychotic activity. Savoxepin mesylate selectively blocks dopamine D2 receptors in the hippocampus while having no significant effect on D2 receptors in the striatum. This selective blockade helps reduce the risk of extrapyramidal side effects (EPS) [1].
Product Specifications
CAS Number
79262-47-8
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/savoxepin-mesylate.html
Smiles
N#CC1=CC=C2OC3=CC=CC=C3C(CCN(CC4)CC5CCCC5)=C4C2=C1.CS(=O)(O)=O
Molecular Formula
C26H30N2O4S
Molecular Weight
466.59
References & Citations
[1]Bischoff S, et al. Blockade of hippocampal dopamine (DA) receptors: a tool for antipsychotics with low extrapyramidal side effects. Prog Neuropsychopharmacol Biol Psychiatry. 1988;12 (4) :455-67.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Frequently Asked Questions
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