GGFG-amide-glycol-amide-Exatecan
GGFG-amide-glycol-amide-Exatecan (Intermediate 2) is an Exatecan (HY-13631) derivative and can be used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[2866301-18-8]
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC; Topoisomerase
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ggfg-amide-glycol-amide-exatecan.html
Purity
98.73
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NCC(NCC(N[C@@H](CC1=CC=CC=C1)C(NCC(NCOCCOC(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O)=O)=O)=O)=O
Molecular Formula
C43H47FN8O11
Molecular Weight
870.88
References & Citations
[1]Marija VRLJIC, et al. Exatecan derivatives and antibody-drug conjugates thereof. WO2022236136A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Camptothecins
Available Sizes
Explore Other Products
Browse additional items from our catalog
E3 ubiquitin-protein ligase RNF125 (RNF125) Human ELISA Kit
CBX8, CT (Chromobox Protein Homolog 8, Polycomb 3 Homolog, Pc3, HPC3, Rectachrome 1, PC3, RC1) (MaxLight 650)
CBX8, CT (Chromobox Protein Homolog 8, Polycomb 3 Homolog, Pc3, HPC3, Rectachrome 1, PC3, RC1) (MaxLight 650)