GGFG-amide-glycol-amide-Exatecan
GGFG-amide-glycol-amide-Exatecan (Intermediate 2) is an Exatecan (HY-13631) derivative and can be used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[2866301-18-8]
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC; Topoisomerase
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ggfg-amide-glycol-amide-exatecan.html
Purity
98.73
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
NCC(NCC(N[C@@H](CC1=CC=CC=C1)C(NCC(NCOCCOC(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O)=O)=O)=O)=O
Molecular Formula
C43H47FN8O11
Molecular Weight
870.88
References & Citations
[1]Marija VRLJIC, et al. Exatecan derivatives and antibody-drug conjugates thereof. WO2022236136A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Camptothecins
Available Sizes
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