Diclofenac epolamine

Flector Patch (Diclofenac epolamine) is a non-steroidal anti-inflammatory drug (NSAID) [1]. Flector Patch is used for relieving arthritis Pain, acute Pain, osteoarthritis, and actinic Keratosis. Flector Patch has good skin absorption characteristics without local adverse reactions and allergies[2].

Product Specifications

CAS Number

[119623-66-4]

Product Name Alternative

Diclofenac hydroxyethylpyrrolidine

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

COX

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cancer

Assay Protocol

https://www.medchemexpress.com/diclofenac-epolamine.html

Purity

99.95

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OCCN1CCCC1.OC(CC(C=CC=C2)=C2NC3=C(C=CC=C3Cl)Cl)=O

Molecular Formula

C20H24Cl2N2O3

Molecular Weight

411.32

Precautions

H302, H315, H319, H335

References & Citations

[1]Del Río-Sancho S, et al. Topical delivery of diclofenac into and across equine skin from a novel liquid diclofenac epolamine formulation. J Vet Pharmacol Ther. 2016 Dec. 39 (6) :578-583.|[2]Fouad SA, Basalious EB, El-Nabarawi MA, Tayel SA. Microemulsion and poloxamer microemulsion-based gel for sustained transdermal delivery of diclofenac epolamine using in-skin drug depot: in vitro/in vivo evaluation. Int J Pharm. 2013 Sep 10;453 (2) :569-78.