(2S) -6-Prenylnaringenin

(2S) -6-Prenylnaringenin is the most efficient compound in forebrain. (2S) -6-Prenylnaringenin acts as a GABAA positive allosteric modulator at α+β- binding interface[1].

Product Specifications

CAS Number

[68236-13-5]

UNSPSC

12352005

Target

GABA Receptor

Type

Natural Products

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/2s-6-prenylnaringenin.html

Purity

99.84

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC1=C2C(O[C@H](C3=CC=C(O)C=C3)CC2=O)=CC(O)=C1C/C=C(C)/C

Molecular Formula

C20H20O5

Molecular Weight

340.37

References & Citations

[1]Ali Y Benkherouf, et al. Hops Compounds Modulatory Effects and 6-prenylnaringenin Dual Mode of Action on GABA AReceptors. Eur J Pharmacol. 2020 Apr 15;873:172962.