Protocatechuic acid

Protocatechuic acid is a phenolic compound which exhibits neuroprotective effect.

Product Specifications

CAS Number

[99-50-3]

Product Name Alternative

3,4-Dihydroxybenzoic acid

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Protocatechuic-acid.html

Purity

99.98

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 10 mg/mL (ultrasonic)

Smiles

O=C(O)C1=CC=C(O)C(O)=C1

Molecular Formula

C7H6O4

Molecular Weight

154.12

Precautions

H315, H319, H335

References & Citations

[1]Thakare VN, et al. Attenuation of acute restraint stress-induced depressive like behavior and hippocampal alterations with protocatechuic acid treatment in mice. Metab Brain Dis. 2016 Oct 26|[2]Adefegha SA, et al. Alterations of Na+/K+-ATPase, cholinergic and antioxidant enzymes activity by protocatechuic acid in cadmium-induced neurotoxicity and oxidative stress in Wistar rats. Biomed Pharmacother. 2016 Oct;83:559-568|[3]Hornedo-Ortega R, et al. Protocatechuic Acid: Inhibition of Fibril Formation, Destabilization of Preformed Fibrils of Amyloid-β and α-Synuclein, and Neuroprotection. J Agric Food Chem. 2016 Oct 10.