Duramycin

Duramycin (Moli1901) is a lantibiotic derived from Streptomyces cinnamoneuma. Duramycin also is a antimicrobial peptide. Duramycin can be used for the research of cystic fibrosis (CF) [1][2].

Product Specifications

CAS Number

[1391-36-2]

Product Name Alternative

Moli1901; Lancovutide

UNSPSC

12352211

Target

Bacterial

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/duramycin.html

Purity

99.46

Solubility

H2O : 0.5 mg/mL (ultrasonic)

Smiles

[CKQCCAFGPF-{Abu}-FVCDGN-{Abu}-K-NH2(Disulfidebridge:Cys1-Abu18,Cys4-Cys14,Cys5-Abu11)]

Molecular Formula

C89H125N23O25S3

Molecular Weight

2013.28

References & Citations

[1]Oliynyk I, et al. Effect of duramycin on chloride transport and intracellular calcium concentration in cystic fibrosis and non-cystic fibrosis epithelia. APMIS. 2010 Dec;118 (12) :982-90.|[2]Huo L, et al. Insights into the Biosynthesis of Duramycin. Appl Environ Microbiol. 2017 Jan 17;83 (3) . pii: e02698-16.