Sisomicin (sulfate)
Product Specifications
UNSPSC Description
Sisomicin sulfate is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin sulfate is highly active against Gram-positive bacteria[1][2][3][4].
Target Antigen
Antibiotic; Bacterial
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Sisomicin-sulfate.html
Purity
99.15
Solubility
H2O : 125 mg/mL (ultrasonic)
Smiles
N[C@H]1[C@](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@@]3([H])OC[C@@](O)(C)[C@H](NC)[C@H]3O)[C@H]2O)([H])OC(CN)=CC1.[2.5H2SO4]
Molecular Weight
692.72
References & Citations
[1]P Noone, et al. Sisomicin, netilmicin and dibekacin. A review of their antibacterial activity and therapeutic use. Drugs. 1984 Jun;27(6):548-78.|[2]Crowe CC, et al. Sisomicin: evaluation in vitro and comparison with gentamicin and tobramycin. Antimicrob Agents Chemother. 1973 Jan;3(1):24-8.|[3]Le Moli S, et al. In vitro and in vivo effect of sisomicin and gentamycin on polymorphonuclear chemotaxis and phagocytosis. Int J Immunopharmacol. 1983;5(1):49-54.|[4]Fabre J, et al. Persistence of sisomicin and gentamicin in renal cortex and medulla compared with other organs and serum of rats. Kidney Int. 1976 Dec;10(6):444-9.ACS Biomater Sci Eng. 2024 Apr 24.|Curr Microbiol. 2021 Dec 14;79(1):12.|Research Square Preprint. 2024 Apr 1.|STAR Protoc. 2024 Jun 7;5(2):103118.|ACS Infect Dis. 2024 Apr 12;10(4):1327-1338.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-B1222/Sisomicin-sulfate-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B1222/Sisomicin-sulfate-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
53179-09-2
Available Sizes
Curated Selection
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