Aquastatin A
Aquastatin A is an inhibitor of mammalian adenosine triphosphatases. Aquastatin A is isolated from a fungus identified as Fusarium aquaeductuum. Aquastatin A inhibits Na+/K (+) -ATPase with an IC50 value of 7.1 μM, and H+/K (+) -ATPase with an apparent IC50 value of 6.2 μM[1].
Product Specifications
CAS Number
[153821-50-2]
UNSPSC
12352005
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/aquastatin-a.html
Purity
90.0
Solubility
10 mM in DMSO
Smiles
CC(C=C1OC(C2=C(C=C(C=C2O)O[C@@H]3O[C@@H]([C@@H]([C@@H]([C@H]3O)O)O)CO)CCCCCCCCCCCCCCC)=O)=C(C(O)=C1)C(O)=O
Molecular Formula
C36H52O12
Molecular Weight
676.79
References & Citations
[1]Hamano K, et al. Aquastatin A, an inhibitor of mammalian adenosine triphosphatases from Fusarium aquaeductuum. Taxonomy, fermentation, isolation, structure determination and biological properties. J Antibiot (Tokyo) . 1993;46 (11) :1648-1657.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
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