What is the catalog number for DMBA?

The catalog number for DMBA is HY-W011845.

What sizes are available for DMBA?

DMBA is available in the following size(s): 50 mg, 100 mg, 250 mg, 1 g.

How many pack sizes does DMBA come in?

DMBA is available in 4 different pack sizes.

DMBA is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures DMBA?

DMBA is manufactured by QuantiMol.

What is the estimated delivery time for DMBA?

Estimated delivery time for DMBA is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for DMBA?

The safety data sheet for DMBA is available here: http://file.medchemexpress.com/batch_PDF/HY-W011845/DMBA-SDS-MedChemExpress.pdf.

DMBA

DMBA has carcinogenic activity as a polycyclic aromatic hydrocarbon (PAH) . DMBA is used to induce tumor formation in various rodent models[1].

Product Specifications

CAS Number

57-97-6

Product Name Alternative

7,12-DMBA; 7,12-Dimethylbenzanthracene

UNSPSC

12352005

Hazard Statement

H302, H350

Target

C-Myc

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/dmba.html

Purity

99.94

Solubility

Acetone : 25 mg/mL (ultrasonic) |DMSO : 12.5 mg/mL|Ethanol : 3.33 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CC(C1=CC=CC=C21)=C3C=CC4=CC=CC=C4C3=C2C

Molecular Formula

C20H16

Molecular Weight

256.35

Precautions

H302, H350

References & Citations

[1]Csiszar A, Balasubramanian P, Tarantini S, Yabluchanskiy A, Zhang XA, Springo Z, Benbrook D, Sonntag WE, Ungvari Z. Chemically induced carcinogenesis in rodent models of aging: assessing organismal resilience to genotoxic stressors in geroscience research. Geroscience. 2019 Apr;41 (2) :209-227. |[2]HUGGINS C, et al., Mammary cancer induced by a single feeding of polymucular hydrocarbons, and its suppression. Nature. 1961 Jan 21;189:204-7.|[3]Goerttler K, et al., Skin tumor formation in the European hamster (Cricetus cricetus L.) after topical initiation with 7,12-dimethylbenz[a]anthracene (DMBA) and promotion with 12-O-tetradecanoylphorbol-13-acetate (TPA) . Carcinogenesis. 1984 Apr;5 (4) :521-4.|[4]Saini RK, et al., Pulmonary carcinogenesis in mice with a single intratracheal instillation of 9, 10-dimethyl benz[a]anthracene. Drug Chem Toxicol. 2008;31 (4) :459-71.|[5]Gao J, et al., Microsomal expoxide hydrolase is required for 7,12-dimethylbenz[a]anthracene (DMBA) -induced immunotoxicity in mice. Toxicol Sci. 2007 Jul;98 (1) :137-44.