Fumaric acid
Fumaric acid is an unsaturated dicarbonic acid, an intermediate product of the citric acid cycle that provides intracellular energy in the form of ATP. Fumaric acid exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway dependent on p38 MAPK. Fumaric acid can be used in the study of pregnancy-induced hypertension[1][2][3].
Product Specifications
CAS Number
110-17-8
UNSPSC
12352211
Hazard Statement
H319
Target
Endogenous Metabolite; NF-κB; p38 MAPK
Type
Natural Products
Related Pathways
MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Fumaric_acid.html
Purity
99.91
Solubility
DMSO : 25 mg/mL (ultrasonic) |H2O : 11.11 mg/mL (ultrasonic)
Smiles
O=C(O)/C=C/C(O)=O
Molecular Formula
C4H4O4
Molecular Weight
116.07
Precautions
H319
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
Human Endogenous Metabolite
Available Sizes
Frequently Asked Questions
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