NSC114792
Product Specifications
UNSPSC Description
NSC114792 is a selective JAK3 inhibitor. NSC114792 induces apoptosis. NSC114792 decreases the protein expression of p-JAK3 and p-STAT5[1].
Target Antigen
Apoptosis; JAK
Type
Reference compound
Related Pathways
Apoptosis;Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nsc114792.html
Smiles
C[C@@]12[C@@H](C(CN3C=NC4=C3N=CNC4=S)=O)CC[C@@]1([H])[C@]5([H])CCC6=CC(CC[C@]6(C)[C@@]5([H])CC2)=O
Molecular Weight
464.62
References & Citations
[1]Kim BH, et al. NSC114792, a novel small molecule identified through structure-based computational database screening, selectively inhibits JAK3. Mol Cancer. 2010 Feb 11;9:36.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-122101/NSC114792-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-122101/
Clinical Information
No Development Reported
CAS Number
17392-79-9
Curated Selection
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