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Gln-AMS

Gln-AMS is an aminoacyl-tRNA synthetases (AARS) inhibitor, which binds the A-domain within the NRPS enzymes.

Product Specifications

CAS Number

209543-57-7

UNSPSC

12352005

Target

Aminoacyl-tRNA Synthetase; Bacterial

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Gln-AMS.html

Purity

98.71

Solubility

DMSO : 120 mg/mL (ultrasonic)

Smiles

NC1=C2N=CN([C@@H]3O[C@H](COS(=O)(NC([C@@H](N)CCC(N)=O)=O)=O)[C@@H](O)[C@H]3O)C2=NC=N1

Molecular Formula

C15H22N8O8S

Molecular Weight

474.45

References & Citations

[1]Fang P, et al. Structural basis for full-spectrum inhibition of translational functions on a tRNA synthetase. Nat Commun. 2015 Mar 31;6:6402.|[2]Atta-ur-Rahman, et al. Frontiers in Natural Product Chemistry.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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