Triacsin C
Product Specifications
UNSPSC Description
Triacsin C (WS 1228A), a natural intracellular long-chain acyl-CoA synthetases (ACSL) inhibitor, is from Streptomyces aureofaciens. Triacsin C inhibits TAG accumulation into lipid droplets (LD) by suppressing ACSL activity[1]. Triacsin C is found to be highly effective against rotavirus replication[2].
Target Antigen
Parasite
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/triacsin-c.html
Purity
99.08
Solubility
DMSO : 5 mg/mL (ultrasonic;warming)
Smiles
CCC/C=C/C/C=C/C=C/C=N/NN=O
Molecular Weight
207.27
References & Citations
[1]Dechandt CRP, et al. Triacsin C reduces lipid droplet formation and induces mitochondrial biogenesis in primary rat hepatocytes. J Bioenerg Biomembr. 2017 Oct;49(5):399-411.|[2]Kim Y, et al. Novel triacsin C analogs as potential antivirals against rotavirus infections. Eur J Med Chem. 2012 Apr;50:311-8.|[3]Guo F, et al. Amelioration of Cryptosporidium parvum infection in vitro and in vivo by targeting parasite fatty acyl-coenzyme A synthetases. J Infect Dis. 2014 Apr 15;209(8):1279-87. |[4]Matsuda D, et al. Anti-atherosclerotic activity of triacsin C, an acyl-CoA synthetase inhibitor. J Antibiot (Tokyo). 2008 May;61(5):318-21.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N6707/Triacsin-C-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N6707/Triacsin-C-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
76896-80-5
Available Sizes
Curated Selection
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