EPHB3 (Phospho Tyr608) rabbit pAb
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. This gene encodes a receptor for ephrin-B family members. [provided by RefSeq, Mar 2010],
Product Specifications
Background
UniProt
P54753
Swiss Prot
P54753
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human EPHB3 (Phospho Tyr608)
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:1000-2000 ELISA 1:5000-20000
Molecular Weight
73kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
73kD
Fragment
IgG
Subcellular Location
Cell membrane ; Single-pass type I membrane protein . Cell projection, dendrite .
Other Product Names
Ephrin type-B receptor 3 (EC 2.7.10.1; EPH-like tyrosine kinase 2; EPH-like kinase 2; Embryonic kinase 2; EK2; hEK2; Tyrosine-protein kinase TYRO6)
Gene ID (Human)
2049
Available Sizes
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