5-PA-dUTP
Product Specifications
Product Name Alternative
5-Propargylamino-dUTP
UNSPSC Description
5-PA-dUTP (5-Propargylamino-dUTP) is a C5-modified nucleotide and can be incorporated into DNA nanoparticles (DNPs) for photosensitizer delivery[1]. 5-PA-dUTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target Antigen
DNA/RNA Synthesis
Type
Biochemical Assay Reagents
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/5-pa-dutp.html
Purity
98.0
Solubility
H2O : 125 mg/mL (ultrasonic)
Smiles
O=C1N([C@H]2C[C@H](O)[C@@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)O2)C=C(C(N1)=O)C#CCN
Molecular Weight
521.20
References & Citations
[1]Kyoung-Ran Kim, et al.Shaping Rolling Circle Amplification Products into DNA Nanoparticles by Incorporation of Modified Nucleotides and Their Application to In Vitro and In Vivo Delivery of a Photosensitizer. Molecules. 2018 Jul 23;23(7):1833.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-132141/5-PA-dUTP-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-132141/5-PA-dUTP-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
179101-49-6
Available Sizes
Curated Selection
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