Purified Anti-Human CD273 Antibody[24F.10C12]

T cells require a signal induced by the engagement of the T cell receptor and a “co‑stimulatory” signal (s) through distinct T cell surface molecules for optimal T cell activation and tolerance. Members of the B7 superfamily of counter-receptors were identified by their ability to interact with co‑stimulatory molecules found on the surface of T cells. Members of the B7 superfamily include B7-1 (CD80), B7-2 (CD86), B7-H1 (PD-L1), B7-H2 (B7RP-1), B7-H3, and PD-L2 (B7-DC) .

PDL; PD-L; PD-1 ligand; PDCD1 ligand; Programmed death ligand; Programmed cell death 1 ligand; PDCD1L; bA574F; PDCD1LG; B7DC; Btdc; CD273; PD-L2; PDCD1L2; PDL2; bA574F11.2; PDCD1LG2; B7-DC; Butyrophilin B7-DC; Programmed cell death 1 ligand 2; PD-1 ligand 2; PDCD1 ligand 2; Programmed death ligand 2; PDL2; PD-L2; B7 dendritic cell molecule; Butyrophilin B7 DC; Butyrophilin B7DC; CD 273; CD273 antigen; MGC142238; MGC142240; PD 1 ligand 2; PD L2; PD1 ligand 2; PD1L2; PDCD 1 ligand 2; PDL 2