Recombinant Human DSG1 Protein
Desmoglein 1 (DSG1), the Pemphigus Foliaceus (PF) antigen, is produced as a precursor (preDSG1) and is transported to the cell surface as the mature form (matDSG1) . Pemphigus foliaceus (PF) is an organ-specific autoimmune cutaneous disease characterized clinically by the development of superficial blisters and erosions of skin, histologically by loss of cell adhesion of keratinocytes in the upper part of epidermis, and immunologically by in vivo bound and circulating IgG autoantibodies directed against desmoglein 1 (Dsg1), a transmembrane desmosomal glycoprotein to the cadherin family.
Product Specifications
Product Name Alternative
DGI, Cadherin family member 4, Desmoglein-1, DG1, Pemphigus foliaceus antigen, CDHF4, DSG1, Desmosomal glycoprotein 1
Accession Number
Q02413
Expression System
Confidential
Nature
Recombinant
Applications
As a diagnostic tool for Pemphigus Foliaceus (PF) .
Stability
Endotoxin
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Form
Lyophilized
Buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping Conditions
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Notes
For research use only.
Species
Homo sapiens (Human)
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