KW-8232

KW-8232, an orally active anti-osteoporotic agent, and can reduces the biosynthesis of PGE2[1].

Product Specifications

CAS Number

[217813-15-5]

UNSPSC

12352005

Target

Prostaglandin Receptor; SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection; GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/kw-8232.html

Purity

98.10

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(N1CCN(CC1)C2=C(Cl)C=CC=C2)C3=C(C(C4=CC=C(C=C4)O)C5=CC=C(C=C5)O)C6=C(N3CCN(C)C)C=CC=C6.O=S(O)(C)=O

Molecular Formula

C37H41ClN4O6S

Molecular Weight

705.26

References & Citations

[1]Uchii M, et al. Effect of KW-8232, a novel anti-osteoporotic agent, on bone loss in sciatic neurectomized rats. Jpn J Pharmacol. 1998 Oct;78 (2) :241-3.|[2]Shiwei Wang, et al. A Transferable Deep Learning Approach to Fast Screen Potent Antiviral Drugs against SARS-CoV-2. bioRxiv. 2020.