Peturadol
NB001 (HTS 09836) is an adenylcyclase 1 (AC1) inhibitor which has effect on neural and non-neural pain by modulating AC1 activity[1].
Product Specifications
CAS Number
686301-48-4
Product Name Alternative
HTS 09836; NB001
UNSPSC
12352005
Hazard Statement
H301
Target
Adenylate Cyclase
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nb001.html
Purity
98.7
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OCCCCCNCCN1C=NC2=C(N)N=CN=C12
Molecular Formula
C12H20N6O
Molecular Weight
264.33
Precautions
H301
References & Citations
[1]Min Zhuo. Method for treating neuronal and non-neuronal pain. US8124599B2.|[2]Wang H, et al., Identification of an adenylyl cyclase inhibitor for treating neuropathic and inflammatory pain. Sci Transl Med. 2011 Jan 12;3 (65) :65ra3.|[3]Zhou Z, et al., Inhibition of calcium-stimulated adenylyl cyclase subtype 1 (AC1) for the treatment of pain and anxiety symptoms in Parkinson's disease mice model. Mol Pain. 2024 Jan-Dec;20:17448069241266683.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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