Peturadol

NB001 (HTS 09836) is an adenylcyclase 1 (AC1) inhibitor which has effect on neural and non-neural pain by modulating AC1 activity[1].

Product Specifications

CAS Number

[686301-48-4]

Product Name Alternative

HTS 09836; NB001

UNSPSC

12352005

Hazard Statement

H301

Target

Adenylate Cyclase

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/nb001.html

Purity

98.7

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

OCCCCCNCCN1C=NC2=C(N)N=CN=C12

Molecular Formula

C12H20N6O

Molecular Weight

264.33

Precautions

H301

References & Citations

[1]Min Zhuo. Method for treating neuronal and non-neuronal pain. US8124599B2.|[2]Wang H, et al., Identification of an adenylyl cyclase inhibitor for treating neuropathic and inflammatory pain. Sci Transl Med. 2011 Jan 12;3 (65) :65ra3.|[3]Zhou Z, et al., Inhibition of calcium-stimulated adenylyl cyclase subtype 1 (AC1) for the treatment of pain and anxiety symptoms in Parkinson's disease mice model. Mol Pain. 2024 Jan-Dec;20:17448069241266683.