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(R) -Praziquantel

(R) -Praziquantel, the active enantiomer of Praziquantel, is a partial agonist of the human 5-HT2B receptor. (R) -Praziquantel acts as an antischistosomal eutomer[1].

Product Specifications

CAS Number

[57452-98-9]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

5-HT Receptor; Parasite

Type

Reference compound

Related Pathways

Anti-infection; GPCR/G Protein; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/r-praziquantel.html

Purity

99.10

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C1CN(C[C@@]2(N1CCC3=C2C=CC=C3)[H])C(C4CCCCC4)=O

Molecular Formula

C19H24N2O2

Molecular Weight

312.41

Precautions

H302, H315, H319, H335

References & Citations

[1]Chan JD, et al. The anthelmintic praziquantel is a human serotoninergic G-protein-coupled receptor ligand. Nat Commun. 2017 Dec 5;8 (1) :1910.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

5-HT2 Receptor; α-1 microglobulin

Available Sizes

Curated Selection

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