(R) -Praziquantel
(R) -Praziquantel, the active enantiomer of Praziquantel, is a partial agonist of the human 5-HT2B receptor. (R) -Praziquantel acts as an antischistosomal eutomer[1].
Product Specifications
CAS Number
[57452-98-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
5-HT Receptor; Parasite
Type
Reference compound
Related Pathways
Anti-infection; GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/r-praziquantel.html
Purity
99.10
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C1CN(C[C@@]2(N1CCC3=C2C=CC=C3)[H])C(C4CCCCC4)=O
Molecular Formula
C19H24N2O2
Molecular Weight
312.41
Precautions
H302, H315, H319, H335
References & Citations
[1]Chan JD, et al. The anthelmintic praziquantel is a human serotoninergic G-protein-coupled receptor ligand. Nat Commun. 2017 Dec 5;8 (1) :1910.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor; α-1 microglobulin
Available Sizes
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