2-Phenylethyl isothiocyanate

2-Phenylethyl isothiocyanate is a potent antifungal agent. 2-Phenylethyl isothiocyanate significantly inhibited spore germination and mycelial growth of Alternaria alternata, with a MIC (minimum inhibitory concentration) of 1.22 mM. The antifungal effect of 2-Phenylethyl isothiocyanate against Alternaria alternate might be via reduction in toxin content and breakdown of cell membrane integrity[1][2].

Product Specifications

CAS Number

[2257-09-2]

Product Name Alternative

2-PE ITC

UNSPSC

12352005

Hazard Statement

H302+H312+H332, H315, H317, H319, H334, H335

Target

Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/2-phenylethyl-isothiocyanate.html

Purity

98.04

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

S=C=NCCC1=CC=CC=C1

Molecular Formula

C9H9NS

Molecular Weight

163.24

Precautions

H302+H312+H332, H315, H317, H319, H334, H335

References & Citations

[1]B. J. Smith, et al. In vitro inhibition of soil microorganisms by 2-phenylethyl isothiocyanate. Plant Pathology. 4 October 2002;51 (5) :585-593.|[2]Zhang M, et al. 2-Phenylethyl Isothiocyanate Exerts Antifungal Activity against Alternaria alternata by Affecting Membrane Integrity and Mycotoxin Production. Toxins (Basel) . 2020 Feb 15;12 (2) :124.