JNJ-17203212
Selected Variant
HY-100129-01
Size: 5 mg
JNJ-17203212 is a selective, potent and competitive TRPV1 antagonist. JNJ-17203212 is developed for researching pain management, such as migraine[1][2].
Product Specifications
CAS Number
821768-06-3
UNSPSC
12352005
Hazard Statement
H301, H319
Target
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/JNJ-17203212.html
Purity
99.94
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(N1CCN(C2=NC=CC=C2C(F)(F)F)CC1)NC3=NC=C(C(F)(F)F)C=C3
Molecular Formula
C17H15F6N5O
Molecular Weight
419.32
Precautions
H301, H319
References & Citations
[1]Xingjuan Chen, et al. Furanocoumarins are a novel class of modulators for the transient receptor potential vanilloid type 1 (TRPV1) channel.J Biol Chem. 2014 Apr 4; 289 (14) : 9600-9610.|[2]Jannis E Meents, et al. Two TRPV1 receptor antagonists are effective in two different experimental models of migraine. J Headache Pain. 2015; 16: 57.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TRPV1
Available Sizes
Price
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