What is the catalog number for GC-7?

The catalog number for GC-7 is HY-108314.

What sizes are available for GC-7?

GC-7 is available in the following size(s): 1 Each.

GC-7 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures GC-7?

GC-7 is manufactured by QuantiMol.

What is the estimated delivery time for GC-7?

Estimated delivery time for GC-7 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for GC-7?

The safety data sheet for GC-7 is available here: http://file.medchemexpress.com/batch_PDF/HY-108314/.

GC-7

GC7 Sulfate is a deoxyhypusine synthase (DHPS) inhibitor.

Product Specifications

CAS Number

150333-69-0

UNSPSC

12352211

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/gc-7.html

Solubility

10 mM in DMSO

Smiles

NC(NCCCCCCCN)=N

Molecular Formula

C8H20N4

Molecular Weight

172.27

References & Citations

[1]Bandino A, et al. Deoxyhypusine synthase (DHPS) inhibitor GC7 induces p21/Rb-mediated inhibition of tumor cell growth and DHPS expression correlates with poor prognosis in neuroblastoma patients. Cell Oncol (Dordr) . 2014 Dec;37 (6) :387-98.|[2]Lou B, et al. N1-guanyl-1,7-diaminoheptane (GC7) enhances the therapeutic efficacy of doxorubicin by inhibiting activation of eukaryotic translation initiation factor 5A2 (eIF5A2) and preventing the epithelial-mesenchymal transition in hepatocellular carcinoma cells. Exp Cell Res. 2013 Oct 15;319 (17) :2708-17.