SC57666

SC57666 is a selective COX2 inhibitor with an IC50 of 26 nM.

Product Specifications

CAS Number

[158959-32-1]

UNSPSC

12352005

Target

COX

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Neuroscience-Neuromodulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/SC57666.html

Concentration

10mM

Purity

98.94

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=S(C1=CC=C(C2=C(C3=CC=C(F)C=C3)CCC2)C=C1)(C)=O

Molecular Formula

C18H17FO2S

Molecular Weight

316.39

References & Citations

[1]Reitz DB, et al. Selective cyclooxygenase inhibitors: novel 1,2-diarylcyclopentenes are potent and orally activeCOX2 inhibitors. J Med Chem. 1994 Nov 11;37 (23) :3878-81.|[2]Riendeau D, et al. Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX2 inhibitor. Br J Pharmacol. 1997 May;121 (1) :105-17.