Activated Protein C (390-404), human

Activated Protein C (390-404), human is a peptide of the activated protein C (a vitamin K-dependent serine protease), potently inhibits APC anticoagulant activity[1].

Product Specifications

CAS Number

[146340-20-7]

UNSPSC

12352209

Target

Ser/Thr Protease

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/activated-protein-c-390-404-human.html

Purity

99.71

Solubility

H2O : 0.5 mg/mL (ultrasonic)

Smiles

OC([C@H](CC1=CN=CN1)NC([C@H]([C@@H](C)CC)NC([C@@H](NC([C@H](CC(O)=O)NC([C@H](CC(C)C)NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@H](CO)NC([C@H](C(C)C)NC([C@H](CCCCN)NC([C@H]([C@H](O)C)NC([C@@H](NC([C@H](C(C)C)NC(CNC([C@@H](N)CC2=CC=C(C=C2)O)=O)=O)=O)CC3=CC=C(C=C3)O)=O)=O)=O)=O)=O)=O)CC4=CC=C(C=C4)O)=O)=O)=O)CC5=CNC6=CC=CC=C56)=O)=O)=O

Molecular Formula

C91H130N22O23

Molecular Weight

1900.14

References & Citations

[1]Mesters RM, et al. Identification of a sequence of human activated protein C (residues 390-404) essential for its anticoagulant activity. J Biol Chem. 1991 Dec 25;266 (36) :24514-9.