CW2158
CW2158 (Compound 13) is a modulator for exportin1 (XPO1), which disrupts the chromatin binding, inhibits NFAT transcription factors and activation of T cells[1].
Product Specifications
UNSPSC
12352005
Target
CRM1
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cw2158.html
Solubility
10 mM in DMSO
Smiles
FC(F)(F)C(N=C1NN2C(C=C(C)C2=O)=O)=NC3=C1C(F)=CC=C3
Molecular Formula
C14H8F4N4O2
Molecular Weight
340.23
References & Citations
[1]Chen YF, et al., Targeting the chromatin binding of exportin-1 disrupts NFAT and T cell activation. Nat Chem Biol. 2024 Mar 25.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Mouse Monoclonal IL18R1 Antibody (B-E43) [PE]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
